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KMID : 1143420200130181217
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Public Health Weekly Report
2020 Volume.13 No. 18 p.1217 ~ p.1230
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Research for Influenza Vaccine Safety Profile among Pregnant Women and International Surveillance of Adverse Events after Influenza Vaccination in Pregnant Women
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Kim Nok-Hyun
Kim Jong-Hee
Ko Hyun-Sun
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Abstract
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Every year, seasonal influenza epidemics infect up to 30% of the population and a relevant portion are hospitalized.
Pregnant women are at greater risk for influenza-related complications than the general population. As a result, a free
national influenza immunization program was planned for pregnant women in Korea during the flu season of 2019-2020.
Although the World Health Organization (WHO) and health authorities in most countries recommend that pregnant women
receive the inactivated influenza virus vaccine, coverage is still limited. As several studies demonstrated, maternal
vaccination against influenza was shown to prevent influenza-like illness in women and infants. However, like other
medications, vaccines are imperfect and may have associated risks. Therefore, national public health officials and the public health community must constantly monitor vaccine-related adverse events, assess risk, and inform the public of any harmful effects. This study aimed to analyze updated pregnancy outcomes after influenza vaccination during pregnancy, and investigate surveillance and compensation claims for adverse events following immunization (AEFI) in other countries. The results of this research contribute to providing a uniform and systematic management of safety, adverse events, and vaccination injur y compensation schemes for pregnant women. The results of this research suppor t policy recommendations and reassure both health care providers (HCPs) and consumers about the safety of vaccination during pregnancy. Further studies about improving knowledge and acceptability of HCPs and pregnant women and legal regulation about AEFI in pregnant women need to follow.
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KEYWORD
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Pregnancy, Influenza, Vaccination, Safety, Surveillance
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